Cytochrome P450 (CYP) enzymes are mainly expressed in the liver and play a key role in driving the metabolism of various compounds in the body. CYPs play an important role in metabolizing external drugs and decomposing and excreting them from the body, and these enzymes determine the efficacy, side effects, and metabolic rate of specific drugs through their interactions. In addition, these enzymes are utilized in various in vitro ADME studies.

SPMED™ Human Recombinant Cytochrome P450 (CYP) Enzymes are produced through the baculovirus expression system and provide mutant forms and various CYP isoforms. This enables accurate and consistent results in the field of drug research and development.

Features

* High enzyme activity

* Provides information on metabolite formation over time

* Uses Baculovirus/insect cell expression system

* Provides various CYP products including FDA-recommended drug metabolizing enzymes CYPs